Feasibility of implantation of a cemented femoral stem in the treatment of osteoporotic femoral neck fracture in elderly patients:study protocol of a randomized controlled trial
Ren Rong
Li Ling-wei
Guo Qi-fa
Abstract：BACKGROUND:Osteogenesis is a common problem after surgery for femoral neck fracture in elderly patients. Internal fixation for the treatment of femoral neck fracture should be performed to optimize bone remodeling and strengthen fractured bone trabeculae, with the aim of achieving strong fixation from the perspective of biomechanics. Percutaneous internal fixation with cannulated compression screws has become a preferred treatment method of osteoporotic femoral neck fracture in elderly patients, but the insufficient holding power of the screws used in the femoral neck does not lead to strong fixation. An alternative, joint prosthesis, is recommended for the repair of femoral neck fracture in elderly patients. However, its long-term therapeutic effects in the treatment of osteoporotic fracture of proximal femoral neck remain poorly understood in patients with avascular necrosis of the femoral head. <br> OBJECTIVE:To investigate the the safety and effectiveness of implantation of cemented femoral stem versus percutaneous internal fixation with cannulated compression screws in the treatment of osteoporotic femoral neck fracture in elderly patients. <br> METHODS:A single-center, prospective, randomized control ed, open-label trial wil be performed in Qinghai University Affiliated Hospital, Qinghai, China. One hundred patients with avascular necrosis of the femoral head complicated by osteoporotic femoral neck fracture wil be randomly assigned to two groups. Group 1 wil undergo percutaneous internal fixation with cannulated compression screws (n=50) and group 2 wil be implanted with cemented femoral stem (n=50). This study protocol has been approved by the <br> Medical Ethics Committee of Qinghai University Affiliated Hospital in China and wil be performed in accordance with the guidelines of the Declaration of Helsinki, formulated by the World Medical Association. Signed informed consent regarding trial procedure and treatment wil be obtained from each patient or
Machine-generated Keywords：
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 7261-7266 )