Mental health status of relative donors versus unrelated donors before and after hematopoietic stem cell collection
Hou Yan-hong
Zhao Shu-yan
Qi Qinjiazi
Liu Li-hui
Chen Xiao-fei
Shi Bing
Zhu Ling
Xu Chen
Jia Rui-ming
Wang Wei-wei
Yang Jing
Liang Yong-qing
Tan Yi
Li Fu-xing
Ye Li-ping
Abstract：BACKGROUND:Currently, hematopoietic stem celltransplantation mainly depends on unrelated donors. Mental state of the unrelated donors is very important to ensure the successful celltransplantation. OBJECTIVE:To compare mental and physical health status of relative and unrelated donors during the hematopoietic stem cellcol ection. METHODS:We compared the mental (Symptom Checklist-90) and physical (temperature, breath, pulse, and blood pressure) health status of relative and unrelated donors at admission, 1 day before cellcol ection, and 1-2 days after cellcol ection.RESULTS AND CONCLUSION:At admission, there was no difference in the mental health status of relative and unrelated donors (P>0.05), while the scores on Symptom Checklist-90 were significantly higher in the unrelated donors than the relative donors, including total score, forced, depression, anxiety, hostility, and fear (P<0.05). The physical signs were steady in the unrelated and relative donors, but the difference in breath and systolic blood pressure was of great significance before and after cellcol ection in the two groups. These findings indicate that during cellcol ection, the unrelated donors exhibit heavier mental load than the relative donors, and psychological counseling and health guidance are necessary.
Keywords：hematopoietic stem celltransplantationstresspsychologicalfearanxiety
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 4524-4529 )