Reactions of the application of neuronavigation system on surgical resection of adult supratentorial glioma and the neuroprotective function

doi:10.3321/j.issn:1673-8225.2004.16.018

Abstract：BACKGROUND: The extent of surgical resection of glioma is closely relating with the prognosis.Neuronavigation system could trace and direct dimensionally to improve the surgical quality of carcinoma excision by clearing the accurate imaging anatomic position of the surgical field for the operator.OBJECTIVE: To apply nerve navigation system in the operation of total resection of adult supratentorial glioma and the function of neural protection.SETTINGS and PARTICIPANTS: Settings: Department of neurosurgery of Beijing Tiantan Hospital. Participants: 85 cases of supratentorial glioma admitted from December 1997 to June 2000, in which there were 51 males and 34females aged from 17 to 56 years old with a diameter of tumour of 1.8 -7.0cm, were selected.INTERVENTIONS: All authors were intervenors. Total resection was operated in all patients under the instruction and the surveillance of navigation system.the limb motor function and language function in postoperative patients.RESULTS: There were 76 cases with total resection, 5 cases with nearlytotal resection and 4 cases with resection in most of the part of the tumour. There were 49 cases had obvious postoperative nerve impairment,which manifested with different extent of limb paralysis and/or languageimpairment and incomplete hemianopia; however, all cases were recoveredwithin 2 months with no permanent nerve impairments. The symptoms significantly improved within short periods after the surgery in all 8 cases withpreoperative hemiplegia, which all were able to walk, and the Karnofaky(KPS) score increased from preoperative 60-70 points to postoperative80 - 90 points.CONCLUSION: From the imaging point of view, it could totally resectgliomas on different sites of cerebral hemisphere in most of the patient byapplying neuronavigation system and moreover, no permanent postoperativenerve impairment would be induced as well.