Relationship between antiphospholipid antibodies and migraine related cerebral infarction
Abstract：AIM:To study the relationship between migraine and cerebral infarction, and also to explore whether anticardiolipin antibodies(ACA) play a role in the mechanisms of migraine-related cerebral infarction.
METHODS:Patients with cerebral infarction and control subjects received a questionnaire that is mainly relative to migraine history.Besides,the patients with cerebral infarction also received sera IgG-ACA detection of enzyme-linked immunoadsordent assay(ELISA).
RESULTS:Twenty percent patients had a history of migraine,while only 6.0% of the control subjects had the incidence of migraine.They had statistically significant difference(χ 2=13.2671,P< 0.01) .The patients with cerebral infarction were divided into two groups:patients with migraine history and patients without migraine history.The positive rates of ACA in the stroke patients with migraine history and that of those without migraine history were 41.67% and 19.5% respectively. They also had statistically significant difference(χ 2=5.0133,P< 0.05) .
CONCLUSION:The study suggested that migraine history was relative to cerebral infarction and ACA might play an important role in the mechanisms of migraine related cerebral infarction.
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Publication Date：2004-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1342-1343 )