Functional evaluation of microporous acellular xeno-dermis matrix transplanted onto burn wound
Abstract：AIM:To observe the clinical effect of the compound skin graft composed acellular xeno- dermis matrix(ADM) and autologous skin. METHODS: The full thickness burn wounds were closed with porous ADM combined with all kinds of autologous skin grafts such as ultrathin,meshed or micronized skin etc.The survival rates of overlying autografts were observed.Pigmentation and elasticity or pliability of the composite skin grafted sites were compared with that covered with simple autografts. RESULTS:Survival rate of microporous ADM combined with ultrathin,meshed or stamp- like skin grafts was 100% ,however that was poor when ADM combined with micronized autografts.The composite skin grafted sites had good wound healing quality including low pigmentation,better elasticity and pliability,compared with that covered with autologous skin without ADM. CONCLUSION: Microporous ADM has intact base membrane structure and regular collagen fiber.The dermal layer can be reconstructed,which improve the wound ducitility and elasticity.It is a good kind of dermal substitutes.
Machine-generated Keywords：
Publication Date：2003-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 4311-4313 )