"Kidney producing medulla"and functions of central nervous system
Abstract：AIM:To explore the entity of " kidney producing medulla" from the angle of neurophysiology and to provide scientific basis for this theory. METHODS:2.5-month old male SD rats were randomly divided into control,castration and vacuity taxation groups.The auditory brainstem response (ABR), sensory evoked potential (SEP), as well as amino acid and monoamine transmitters in brain were used as markers for functional states in rats models of castration kidney vacuity and vacuity taxation kidney vacuity. RESULTS:Testosterone(T) level in two " kidney vacuity" model rat 's blood dropped.The thymus mass in vacuity taxation group[(271± 20) mg] was significantly lower than that in control group[(565± 81) mg,P< 0.01].For function conditions of sensory nervous system,there is a prolonged (delayed) peak latency of ABR(F=6.713,P< 0.001),and SEP(F=4.161, P=0.002), a risen threshold of ABR(F=9.555, P< 0.001); The differences were significant.The amino acid and monoamine transmitters levels in brain were lower than control group, except GABA in castration group's. CONCLUSION:Low blood T level in kidney vacuity will affect excitability of CNS,which might be resulted in by the regulation of kidney(gonadal hormone) on synthesis and release of some central transmitters.
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Publication Date：2003-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 3027-3029 )