Expression of estrogen receptor β and the accommodate of sexual function

doi:10.3321/j.issn:1673-8225.2003.15.012

Abstract：Aim To investigate the distribution expression of estrogen receptor β (ERβ )sub-type in mouse developing processes and the accommodate of sexual function. Our research observed the expressing and distribution of ERβ in 1, 2, 3, 4 weeks mice testis after born and adult mouse. Methods Male Kunming mouse 1 , 2 , 3 , 4 week after born during the development procedure and adult male kunming mouse, altogether 12, were divided into 2 groups. Immunohistochemistry and Fluorescence-immunohistochemistry staining were used to test ERβ in mouse testis . Results In ages of 1,2,3,4 weeks and adult mouse testis, we found that estrogen receptor β distributed in Leydig cells of testis. And the number of immunoreativity positive cells was increasing as developing. The immunoreactivity products were all in cell plasma. Products in adult mice testis were more intensive than immature little mice. Conclusion ERβ is special characteristic receptor which regulate and affect andrology endocrining and semen generate function and spermatozoon mature. In every stages of development, they appear most frequently and show their affect on generating processes and sperm cell development.