Study of the blood lipids levels with coronary heart disease in the races of the Uygur and the Hans in Xinjiang, China

doi:10.3321/j.issn:1673-8225.2003.09.001

Abstract：Aim Dyslipidemia has been identified as the primary risk factor leading to the development of coronary heart disease (CHD). The lipids changes and differences in the races of the Uygur and the Hans with coronary heart disease (CHD) were studied for researching the relationship of the lipids.Methods Serum lipids were measured including total cholesterol(TC),high- density lipoprotein cholesterol (HDL- C), low- density lipoprotein cholesterol (LDL- C),and triglyceride (TG) as well as fasting blood glucose (FG) in the races of the Uygur and the Hans compared with 167 control persons (75 of them in the Uygur and 92 of them in the Hans) and in 487 subjects with CHD who were 245 subjects in the Uygur, and the others in the Hans. Age and sex in groups are comparable.Results The subjects in the Uygur had higher levels of TC,LDL- C,TG and FG(q=10.01,12.69,4.45,6.78;P< 0.01), and lower level of HDL- C in comparison with the controls (q=6.95,P< 0.01).Some similar differences were in the Hans (q=10.06,11.89,6.35,5.96, 9.82;P< 0.01). But changes in the serum lipids and FG showed no significant difference between the two ethnic groups (q=0.35- 1.41,P >0.05). Conclusion Dyslipidemia (elevated TC and LDL- C, reduced HDL- C, raised TG) and higher blood glucose are the risk factors of the two races with coronary heart disease (CHD).