Change and significance of gfap in the brain of mice exposed to infrasound
Abstract：Objective To study the change and significance of GFAP in thebrain of the mice exposed to infrasound of different sound pressure level .Method The BALB/C mice were exposed to infrasound of 16Hz with intensity of 90dB and 130dB for 1,7,14,21and 28 days. It was for 2h every day. Then immunohistochemical technique was exployed to detect the change of GFAP in the brain of the mice. Results The expression of GFAP increased mainly in the hippocampus,cortex and hypothamus regions after infrasound of 90dB and 130dB exposed .The effect at 130dB infrasound was more than 90dB.Conclusion The extent of GFAP change is closely related to the action times under infrasound of same sound pressure level. Infrasound bring about brain injury through the change of GFAP in the brain, which is one of the important factors that infrasound cause brain injury.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 45,90 )