Clinical Study on Modified Local Anesthesia for Transurethral Incision of the Prostate(TUIP)in Elderly Patients with Multiple Comorbidities
Guo Naichao
Zuo Shidong
Dong Yuhao
An Lin
Lyu Yanlin
Wang Yong
Abstract：Methods A retrospective cohort study was conducted,and 195 elderly BPH patients with multiple comor-bidities who underwent surgical treatment in the Department of General Surgery,the 982nd Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from June 2022 to November 2024 were included.Among them,65 patients underwent surgery under modified local anesthesia(LA group)and 130 patients under traditional epidural anesthesia(control group).After propensity score matching at a 1:1 ratio,there were 60 patients in each group.General clinical data,surgery-related safety and efficacy data were analyzed.Paired samples t-test was used for comparison of measurement data be-tween groups,paired rank sum test for ranked data,and McNemar test for count data.Results The baseline data of the two groups were comparable.In terms of safety indicators,the length of hospital stay in the LA group was significantly shorter than that in the control group(P<0.001),while there were no statistically significant differences in operation time,intraop-erative vital signs of patients,Visual Analogue Scale(VAS)pain score,and postoperative adverse events between the two groups(P>0.05).In terms of efficacy indicators,there were no statistically significant differences between the two groups[improvement in International Prostate Symptom Score(IPSS):P=0.817;improvement in maximum urinary flow rate(Qmax):P=0.950].Conclusion TUIP under modified local anesthesia is safe and effective for elderly BPH patients with multiple comorbidities.Due to the change in anesthesia method,it is more tolerant to patients'underlying diseases,enabling rapid postoperative recovery and discharge,which is conducive to patients receiving surgical treatment more safely and conve-niently.Objective To explore the safety and efficacy of transurethral incision of the prostate(TUIP)under modified local anesthesia in the treatment of elderly patients with benign prostatic hyperplasia(BPH)and multiple comorbidities.
Keywords：benign prostatic hyperplasia local anesthesiaelderly patients with multiple comorbiditiestransurethral incision of the prostate
Publication Date：2025-12-28
Online Publishing Date：2026-03-11(First online date of this platform, not the publication date of the document)
Pages：5( 402-406 )