Analysis of Operative Effect and Influencing Factors in Patients With Non-Functioning Adrenal Adenomas Complicated With Hypertension
Guo Linfa
Liu Tongzu
Hu Dongliang
Abstract：Objective:To investigate the surgical outcomes and influencing factors in patients with non-function-ing adrenal adenomas(NFAs)and hypertension.Methods:A retrospective analysis was conducted on 123 patients with NFAs and hypertension who underwent surgical treatment at the Department of Urology,Zhongnan Hospital of Wuhan University from January 2021 to March 2023.Follow-up observations were made to assess the improvement in blood pressure after surgery.Patients were divided into two groups based on postoperative blood pressure:the inef-fective group and the effective group.Clinical characteristics and the efficacy of hypertension treatment were analyzed to identify the factors influencing postoperative blood pressure improvement.Results:All 123 patients successfully underwent laparoscopic surgery,with 114 undergoing partial adrenalectomy and 9 undergoing unilateral total adrenal-ectomy.Postoperative follow-up showed that 71 patients(57.7%)experienced an improvement in their hypertension.Analysis of clinical characteristics revealed statistically significant differences in body mass index(BMI)and the dura-tion of hypertension between the ineffective and effective groups(P<0.05).Conclusion:Surgical treatment can im-prove blood pressure levels in some patients with NFAs and hypertension.BMI and the duration of hypertension are independent factors influencing postoperative blood pressure improvement.
Keywords：nonfunctioning adrenal adenomahypertensionbody mass indexduration of hypertension
Publication Date：2025-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 145-149 )