Clinical Efficacy and Safety of Laparoscopic Renal Cyst Decapsulation Combined with Ureteroscopic Thulium Laser Cyst Decapsulation for the Treatment of Polycystic Kidney Disease
Gu Tengfei
Chen Ting
Pan Yongtao
Li Jie
Abstract：Objective:To investigate the efficacy and safety of laparoscopic renal cyst decapsulation combined with ureteroscopic thulium laser cyst decapsulation for the treatment of polycystic kidney disease(PKD).Methods:A retrospective analysis was performed on 40 patients who underwent surgical treatment for polycystic kidney disease at the Department of Urology,Lishui Central Hospital,between October 2021 and December 2023.Of these,15 pa-tients received laparoscopic renal cyst decapsulation combined with ureteroscopic thulium laser cyst decapsulation(ob-servation group),while 25 patients underwent only laparoscopic renal cyst decapsulation(control group).The gener-al data,surgical characteristics,renal function changes,local symptoms,and quality of life were compared between the two groups.Results:Pathology results for both groups indicated benign renal cysts,with some patients showing inflammatory changes.Three months postoperatively,the kidney volume on the surgical side had significantly re-duced in both groups compared to preoperative levels(P<0.05),with the reduction being more significant in the ob-servation group than in the control group(P<0.05).At 3 and 6 months postoperatively,the observation group showed greater improvement in serum creatinine,glomerular filtration rate(GFR)of the affected kidney,and blood pressure compared to the control group(P<0.001).The observation group also had significantly greater relief of flank pain,improved quality of life,and better management of large cysts on the affected kidney compared to the con-trol group(P<0.05).The observation group had a longer operative time than the control group(P<0.05).There were no significant differences between the two groups regarding intraoperative blood loss,postoperative infection rates,postoperative hospital stay,or incidence of postoperative fever(P>0.05).Conclusion:Laparoscopic renal cyst decapsulation combined with ureteroscopic thulium laser cyst decapsulation offers more thorough cyst treatment,greater improvement in renal function and blood pressure,as well as better relief of local symptoms and quality of life,compared to simple laparoscopic decapsulation.This approach does not increase surgical risk or perioperative complications and is worthy of clinical promotion.
Keywords：polycystic kidney diseaselaparoscopic renal cyst decapsulationureteroscopic thulium laser cyst decapsu-lationthulium laser
Publication Date：2024-12-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 365-371 )