Application of the Contralateral Suppression Index in Diagnosing the Functional Dominant Side in Bilateral Adrenal Adenomas
Yan Chengquan
Wang Pengfei
Yin Guangwei
Zhao Chaofei
Meng Xin
Zhang Peng
Meng Bin
Li Lin
Li Zangtuo
Zhang Weitao
Cai Shengyong
Sun Hongtian
Yin Huaifu
Abstract：Objective:To explore the application value of the contralateral suppression index(CSI)in determin-ing the dominant side in patients with bilateral adrenal adenomas who experience failure of unilateral adrenal venous sampling(AVS).Methods:We summarized the basic data of patients who underwent adrenal venous sampling for bilateral adrenal adenomas at Tangshan Workers'Hospital from August 2022 to February 2024.A retrospective anal-ysis was conducted on 5 patients who failed unilateral adrenal venous sampling and determined the dominant side us-ing the contralateral suppression index.The basic information of these patients(sex,age,hypertension history,pres-ence of hypokalemia,and admission blood pressure),laboratory findings,and pathological data were reviewed.Fol-low-up data on treatment outcomes were also collected.Results:In all 5 patients,right-sided adrenal venous sam-pling failed(lateralization index[LI]<2).The dominant side was determined using the left-sided contralateral sup-pression index,and all patients achieved favorable clinical outcomes postoperatively.This indicates that the contralat-eral suppression index can provide valuable information for determining the dominant side in cases where unilateral ad-renal venous sampling fails.Conclusion:The contralateral suppression index has significant clinical application value in determining the dominant side in bilateral adrenal adenomas,particularly when unilateral adrenal venous sampling fails.It can serve as a useful reference for selecting the surgical side.
Keywords：Primary aldosteronismbilateral adrenal adenomasadrenal venous samplingcontralateral suppression in-dex
Publication Date：2024-12-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 361-364 )