Quantitative evaluation of renal blood perfusion by contrast-enhanced ultrasound in percutaneous nephrolithotomy
Tian Jisong
Li Shoupeng
Mai Haixing
Shen Donglai
Wang Wei
Chen Hairui
Zhang Xu
Li Qiuyang
Luo Yukun
Abstract：Objective:To investigate the value of quantitative evaluation of renal blood perfusion by contrast-en-hanced ultrasound(CEUS)in percutaneous nephrolithotomy(PCNL).Methods:A total of 21 renal stone patients with PCNL who underwent double contrastus-guided PCNL at the First Medical Center of the PLA General Hospital from January 2024 to April 2024 were prospectively included.CEUS examinations were performed 2 days before sur-gery and 2 weeks after surgery.The differences of imaging parameters[peak intensity(PI),time of arrival(AT),time of peak arrival(TTP)and area under the curve(AUC)]between the renal cortex in stone compression area and non-stone compression area before PCNL,the renal cortical angiography parameters in stone compression area before and after PCNL,and the contrast parameters of renal cortex in stone compression area and non-stone compression ar-ea after PCNL were compared.Statistical methods were analyzed by Matched samples t-test and paired samples Wil-coxon signed rank test,et al.Results:Before PCNL,the PI and AUC of renal cortex in the stone compression area were significantly lower than those in the non-stone compression area,AT and TTP were higher than those in non-calculus compression area,and the differences were statistically significant(all P<0.05).After PCNL,the PI and AUC of renal cortex were significantly higher than those before operation,with statistical significances(all P<0.001),but there was no significant difference in the AT or TTP compared with those before operation(P>0.05).There was no significant difference in the PI or AUC of the renal cortex in the stone compression area after PCNL compared with that in the non-stone compression area(P>0.05),the differences of renal cortex AT and TTP in stone compression area were statistically significant compared with that in non-stone compression area(all P<0.05).Conclusion:PCNL can significantly improve the intrarenal blood perfusion after the removal of kidney stones.CEUS has important clinical significance in the evaluation of local renal function,the efficacy of PCNL and follow-up postop-erative renal function.
Keywords：contrast-enhanced ultrasoundpercutaneous nephrolithotomyblood perfusion
Publication Date：2024-08-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 235-239 )