Clinical efficacy evaluation of 450nm blue laser vaporization in the treatment of high-risk patients with benign prostatic hyperplasia
Zhang Dongbang
Hu Sen
Liu Wei
Yan Xuedong
Xie Xiujuan
Abstract：Objective:To assess the clinical efficacy of transurethral blue laser vaporization using a 450 nm blue laser semiconductor therapy unit in the treatment of high-risk prostatic hyperplasia(BPH).Methods:A total of 80 BPH patients were enrolled from January to September 2023 at the Department of Urology,Qinghai Red Cross Hos-pital.They were randomly divided into a study group and a control group,with 40 cases in each group.The study group underwent transurethral blue laser vaporization while the control group underwent transurethral resection of prostate(TURP).The two groups were compared for operative time,postoperative bladder irrigation and catheter in-dwelling time,intraoperative and postoperative hemoglobin decline,time to getout of bed after surgery,improve-ment in prostatic symptoms and complications.Results:All 80 BPH patients successfully completed the operation.Eight patients in the TURP group required cystostomy during surgery,whereas no cystostomies were performed in the study group.Compared to the control group,the study group had shorter operative times,less bleeding volume,shorter postoperative bladder irrigation and catheter indwelling time,and earlier time to get out of bed(P<0.05).Both groups showed significant decreases in IPSS and PRV scores as well as significant increases in Qmax values af-ter surgery compared to pre-surgery levels(P<0.05),but there was no significant difference between the two groups regarding IPSS scores,PRV scores or Qmax values after surgery(P>0.05).The overall complication rate was lower than that of the control group(P<0.05).Conclusion:Transurethral blue laser vaporization using a 450 nm blue laser is highly effective for treating BPH with advantages such as efficient hemostasis capability,shorter operative times,low incidence of intraoperative bladder fistula,fewer complications,It effectively reduces bladder irrigation and cathe-terization time,promotes good postoperative voiding,and demonstrates certain advantages in treating high-risk BPH cases.
Keywords：high riskprostate hyperplasiablue lasercurative effect
Publication Date：2024-06-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 183-187 )