Analysis the effect of microwave ablation assisted zero ischemi laparoscopic partial nephrectomy on T1 renal cell carcinoma

Liu Ming; Yu Mingzhu; Zheng Huijie; Chen Yamei; Gao Shiliang; Yu Chunyan; Tan Gongxiang

doi:10.19558/j.cnki.10-1020/r.2024.01.003

Abstract：Objective:To explore the value of microwave ablationassisted zero ischemic laparoscopic partial ne-phrectomy in the treatment of T1 renal cell carcinoma(RC).Methods:106 patients with T1 renal cell carcinoma in our hospital from August 2020 to August 2022 were selectedand divided into A and B group by random number ta-ble,with 53 cases in each group.Microwave ablationassisted zero ischemia laparoscopic partial nephrectomy(MWN-LPN)was performed in group A,and traditional laparoscopic partial nephrectomy(LPN)was performed in group B.Perioperative indicators,complications and tumor recurrence,the third space indicators[sodium(Na+),calcium(Ca2+),potassium(K+),albumin(ALB),prealbumin(PA)],renal function indicators[serum creatinine(Scr),estimated glomerular filtration rate(GFR)],tumor markers[cancer antigen(CA50),CA199,alpha-fetoprotein(AFP)]before and after surgery were compared between the two groups.Results:Compared with group B,group A had higher hemoglobin(Hb),serum Na+,Ca2+,ALB,PA on postoperative day3,Scr and GFR on postopera-tive day3 and day5,and lower K+on day3,with statistical significance(P<0.05).Compared with preoperative,lev-els of serum CA50,CA199,and AFP decreased at 1 and 3 months after operationin both group,and the differences were significant(P<0.05).The incidence rate of complications was lower in group A than that of group B[1.89%(1/53)vs.16.98%(9/53);P<0.05].Conclusion:Both MWN-LPN and traditional LPN can achieve ideal tumor clear-ance effect in the treatment of T1 renal cell carcinoma,but the former has no thermal ischemia phenomenon,which can reduce the influence on the third space effect,reduce postoperative renal injury and reduce the risk of complica-tions.