Exploring the diagnostic value of serum prostate specific antigen combined with biparametric magnetic resonance imaging in primary hospital for prostate cancer
Pan Wei
Fang Jichao
Liu zheng
Lu Yuchao
Cai Heling
Han Lingjun
Abstract：Objective:To evaluate the diagnostic value of primary healthcare institutions utilizing serum pros-tate specific antigen(PSA)combined with biparametric magnetic resonance imaging(bpMRI).Methods:Dataof 307 male patients with elevated PSA undergoing pathologic biopsy were collected from January 2018 to December 2019 in the area of Huangpi.Serum PSA and bpMRI images were retrospectively analyzed,the resultsof pathologic biopsy was the gold standard,and the diagnostic value of serum PSA combinedwith bpMRI images by ROC curves was pre-dictedby received operating characteristic curve(ROC).Results:Among 307 patients screened by serum PSA,132 patients were diagnosed prostate cancer by prostate biopsy,with a detection rate of 42.99%;the higher the serum PSA rise,the higher the positive prostate cancer detection rate;the more pronounced the bpMRI abnormal signal,the higher the positive prostate cancer detection rate.The area under the curve(AUC)was 0.884 with a sensitivity of 0.775 and the iodine index was 0.702 for both assays,both of which were higher than the individual assays,and the specificity of 0.927 was the same for the individual bmMRI imagesassays.Conclusion:PSA combined with bpMRI is of high value in the clinical diagnosis of prostate cancer under limited conditions in primary hospitals.
Keywords：prostatic neoplasmsprostate specific antigenmagnetic resonance imaging
Publication Date：2023-12-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 411-415 )