Progress on PSMA Targeted Radioguided Surgery in The Treatment of Prostate Cancer
Cheng Yang
Pan Chunwu
Xia Xiaoyu
Abstract：Prostate cancer is a common tumor in the male urinary system.The technical improvements of radical prostatectomy is a hot topic in the field of prostate cancer treatment.Radioguided surgery targeting prostate-specific membrane antigen(PSMA-RGS)has enhanced the efficiency to detect and remove micrometastatic lymph nodes dur-ing the radical prostatectomy,potentially improving the prognosis for both primary and recurrent prostate cancer.Cur-rently,various radiolabeled small molecule inhibitors have been appplied in PSMA-RGS,while the recent emergence of the DROP-IN probe has further facilitated the integration of RGS and minimally invasive robot-assisted laparoscop-ic surgery.This paper reviews the progresson PSMA-RGS for prostate cancer treatment,focusing on the optimization of radiolabeled targeted ligands,evolution of surgical techniques,as well as the relevant clinical applications.
Keywords：prostatic neoplasmstargetedradioguided surgeryrobotic surgical procedures
Publication Date：2023-10-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 343-347 )