Efficacy of 1 470 nm diode laser combined with intravesical chemotherapy of apaziquone for superficial bladder tumor
Yang Rongquan
Liao Zeming
Cai Yong
Abstract：Objective:To analyze the clinical curative effect and side effects of 1 470 nm diode laser combined with intravesical chemotherapy of apaziquone for superficial bladder tumor.Methods:Fifty patients with superficial bladder tumor were randomly divided into a group of 1 470 nm diode laser combined with intravesical chemothera-py of apaziquone (combination group)and a group of 1 470 nm diode laser combined with intravesical chemothera-py of pirarubicin (control group).After treatment,the patients in two groups were followed up for 3 6 months, and the tumor recurrence rate,recurrence-free survival time and adverse reactions of chemotherapy were compared between the two groups.Results:The one-year recurrence rate in the combination group and control group was 5 . 36% (3/56)and 19.64% (11/56)respectively,and the 36-month cumulative recurrence rate in the combination group and control group was 8.93% (5/56)and 26.79% (15/56)respectively.The one-year recurrence rate and the 12-36 month cumulative recurrence rate in the combination group were significantly lower than those in the control group (P<0.05).No statistically significant difference was observed in side effects between the combina-tion group and control group (P>0.05).Conclusions:1 470 nm diode laser combined with intravesical chemother-apy of apaziquone for superficial bladder tumor is superior to 1 470 nm diode laser combined with pirarubicin.The apaziquone can decrease recurrence rate,at the meantime,the side effects are easily to be tolerated,and it is wor-thy of wide clinical application.
Keywords：bladder tumorapaziquonepirarubicinintravesical chemotherapydiode laser
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 192-195 )