The spindle renal cell carcinoma: Report of one case and review of literature
Cai Xingjian
Zhang Muchun
Zhang Gang
Zhang Zhuo
Fan Li
Zhang Yun
Zhang Dehua
Kong Xiangbo
Abstract：Objective:To investigate the clinical characteristics,treatment and prognosis of renal spindle cell tumors (RSCTs).Methods:We reported the clinical data of one case of RSCTs,and reviewed related literature.Results:The patient was diagnosed as having left renal pelvic tumor and renal failure according to the preoperative related check,physical examination and medical history.Radical operation of renal pelvic carcinoma was performed in this case,and postoperative pathological findings confirmed the diagnosis of RSCTs.There were positive markers such as VIM(+),CD10(+),EMA (spcial mess +),SMA (partial +),CD34 (vessel +) and Ki67 (30%+),and negative markers such as CK (-),RCC (-),PAX-2 (-),ALK (-) and S-100 (-).The patient died of multiple systemic metastases after 4 months.Conclusions:RSCTs are rare and highly aggressive disease.Their diagnosis relys on pathologic and immunohistochemical examinations.Radical nephrectomy is the primary means in RSCTs,chemotherapy and radiotherapy obtain poor efficacy and the prognosis is poor.
Keywords：kidney neoplasmsrenal spindle cell tumourpathology and immunohistochemistry
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 221-223 )