Strategy in treating synchronous sporadic bilateral renal cell carcinoma
Wang Baojun
Gong Huijie
Zhang Xu
Li Shichao
Li Hongzhao
Ma Xin
Song Erlin
Gao Jiangping
Dong Jun
Abstract：Objective:To discuss the surgical strategy in treating synchronous sporadic bilateral renal cell carci-noma.Methods:Clinical and pathological data of 64 patients with synchronous sporadic bilateral renal cell carcinoma were analyzed retrospectively.Of all the 64 patients,47 patients were males and 17 were females,the mean age was 51 (25-69)years.59 patients without symptoms were diagnosed with bilateral renal cell carcinoma during regular check-up,2 patients presented with hematuria and 3 with backache.None of these patients presented with lymphatic or distant metastasis.38 patients were diagnosed with T1a tumors,17 with T1b and 9 with T2a.Results:All the 64 patients underwent bilateral retroperitoneoscopic surgeries.Of the 4 patients undergoing single procedures,2 pa-tients developed acute renal failure and acquired temporarily hemodialysis.Of the 60 patients undergoing staged pro-cedures,bilateral NSS was performed in 34 patients (NSS-NSS group),RN followed by NSS in 19 patients (RN-NSS group)and NSS followed by RN (NSS-RN group)in 7 patients.The mean sCr of each group after bilateral sur-geries were 89μmol/L,110μmol/L,102μmol/L,respectively.1 patientundergoing bilateral RN required routine hemodialysis.The median follow up time was 49 (7-99)months.50 patients survived without tumor,2 patients de-veloped local recurrence,5 patients suffered from lymphatic or distant metastasis and 7 patients died in the last fol-low up.Conclusions:Retroperitoneoscopic staged NSS was the preferred choice for the management of synchronous sporadic bilateral renal cell carcinoma,which was superior in renal functional preservation with the complete resec-tion of tumors.There was not a significant difference in the prognosis between patients with synchronous sporadic bi-lateral renal cell carcinoma and unilateral renal cell carcinoma.
Keywords：renal cell carcinomasynchronousbilateralretroperitoneoscopic
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 283-285 )