DOI: 10.11958/20252004
MDT treatment strategy for organophosphorus and anticoagulant rodenticide poisoning in an elderly patient with depression
FU Shasha
JIA Yue
SHAO Hongxia
GUO Yu
MA Longyan
HAN Tong
SUN Hao
YU Hongzhi
Abstract：Organophosphorus pesticide(OP)is one of the most widely used pesticides in the world with the largest dosage.Acute organophosphorus pesticide poisoning(AOPP)is a common clinical disease,and AOPP accounts for 20%-50%of poisoning cases in China every year,with case fatality rate of 3%-40%.Bromophos(BDF)is a long-acting anticoagulant rodenticide,which inhibits vitamin K epoxide reductase and interferes with the synthesis of coagulation factorsⅡ,Ⅶ,Ⅸ and Ⅹ,leading to coagulation dysfunction.This article discusses the multidisciplinary diagnosis and treatment(MDT)process of a patient with combined poisoning of dichlorvos and bromadiolone.The article explores blood purification,management of coagulation abnormalities,secondary infection,atropinization and altered consciousnes in patients with organophosphorus poisoning and anticoagulant rodenticide compound poisoning,with the aim of providing clinicians with references for early diagnosis and treatment.
Keywords：organophosphate poisoningblood coagulation disordersconsciousness disorderscoinfectionrodenticide poisoningatropinizationmultidisciplinary diagnosis and treatment
Publication Date：2025-09-15
Online Publishing Date：2025-09-23(First online date of this platform, not the publication date of the document)
Pages：5( 1000-1004 )