DOI: 10.11958/20242336
Effect evaluation of Kushen Huangqi decoction combined with Aidi injection in the treatment of primary liver cancer
YU Guanghua
SONG Chunyan
SONG Xue
Abstract：Objective To investigate the therapeutic effect of Kushen Huangqi decoction combined with Aidi injection on primary liver cancer and its impacts on immune function and quality of life.Methods A total of 110 patients with primary liver cancer were randomly divided into the combined group(n=55)and the control group(n=55).The control group was treated with Aidi injection(50 mL)on the basis of routine treatment,and the combined group was treated with Kushen Huangqi decoction on the basis of the control group.The healing effects,traditional Chinese medicine(TCM)symptom scores,quality of life[Karnofsky Performance Status(KPS)score,the MOS 36-item short-form health survey(SF-36)],liver function indicators[total bilirubin(TBIL),aspartate aminotransferase(AST),alanine aminotransferase(ALT)]and immune function indicators before and after treatment were compared between the two groups.Results After treatment,the KPS score,SF-36 score,CD4+and CD4+/CD8+were increased in the two groups,and those in the combined group were higher than the control group.The TCM symptom scores,AST,TBIL,ALT and CD8+were decreased in the two groups,and those in the combined group were lower than those in the control group(P＜0.05).Conclusion The combination of Kushen Huangqi decoction and Aidi injection is beneficial for enhancing immune function,reducing Chinese medicine syndrome scores and liver function damage,improving efficacy and quality of life in treating primary liver cancer.
Keywords：Ai Di Zhu She Yedrug therapycombinationdrug evaluationquality of lifeKushen Huangqi Decoctionprimary liver cancerimmune function
Publication Date：2025-04-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 429-433 )