DOI: 10.11958/20240117
Progress of the aryl hydrocarbon receptor in inflammatory skin diseases
LIU Haoying
SHI Tianwei
Abstract：The aryl hydrocarbon receptor(AhR),also known as dioxin receptor,is a ligand-dependent transcription factor.Because of its important role in occurrence and development of cancer,it has been widely studied.AhR is now considered to be an important regulator of host-environment interactions in immune and inflammatory responses and is involved in pathogenesis of many skin diseases.Because AhR is highly expressed in all types of skin cells and regulates many genes that are critical to skin function,it has the potential to be a new target for the treatment of inflammatory skin diseases.This paper presents and analyzes research findings on the relationship between AhR and inflammatory skin diseases to help accelerate the development of new drugs.
Keywords：receptorsaryl hydrocarboninflammationskin diseases
Publication Date：2024-11-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1221-1225 )