Study on Expression of EGFR and NM23 in Patients with Gestational Trophoblastic Disease
LIU xiaomei
QU Quanxin
MI Ruoran
Abstract：Objective: To study the role of epithelial growth factor receptor (EGFR) and NM23 in the development of gestational
trophoblastic disease. Methods:The expression of EGFR and NM23 in 82 cases of gestational trophoblastic disease and 10
cases of normal placenta were tested with immunohistochemical method. Results:Compared with hydatidiform mole,the ex-
pression of EGFR and NM23 in malignant trophoblastic tumors was decreased and not associated with the proliferation of
trophoblastic cells. Conclusion:The coincident decreased expression of EGFR and NM23 may play an important role in the
development of trophoblastic tumors.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 275-277 )