Lung Function in Patients with Chronic Obstructive Pulmonary Disease
Abstract：Objective: To find out the laws of variation and deterioration of lung function in patients with chronic obstructive pul
monary disease (COPD). Methods: Thirty-six cases of COPD were studied during 1986-1999. Their lung functions were
tested every one or two years in the periods when their diseases were relieved. The year descending rates of main indexes of
their lung functions were calculated and compared with those of the control group. Results:All main indexes of lung function
in COPD group descended during the 13 years, of which the greatest year descending rate was in MVV [ (6.65 ±
6.28)% ],next in V25/HT, MMF and FEV1 [(6.26 ± 9.11)%, (4.88 ± 3.06)% and (4.60 ± 4.62)% respectively].
Their year descending rates were greater than those of the control group [ (2.61 ± 4.14) %, ( 1.51 ± 4.58) %, (2.50 ±
2.82) % and ( 1.83 ± 3.40) % respectively, P ＜ 0.01 ～ 0.001 ]. Conclusion: The most sensitive index of lung function in COPD group was MMF, followed by MVV, FEV1 and V25/HT. The year descending rate of MMV was not so great as
those of MVV and V25/HT,but it had the least standard deviation, varied greater than that in control group and had no cor
relation with the exertion of subject,so it was a more stable and reliable index reflecting the lung function in COPD.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 269-271 )