Effect of Anti-Thyroid Drug on Heart Rate Variation in Patients with Graves Disease
LI Rong
YAN Zhongde
LIU Dong fang
Abstract：Objective:To study the effect of anti-thyroid drug(ATD)on heart rate variation (HRV)in patients with Graves disease(GD). Methods: The HRV of 24 patients with GD was compared with that of 30 normal subjects and the effects of ATD onHRV of the patients were also evaluated. Results: The prevalence of autoromic neuropathy (AN)in GD before treatment(group I) was about 83.3 % and it was about 12.5 % after treatment (group II). There were significant differences of spec-tral index(TFP,PHV,PVV and RVH)between the group I and the control group,and there was no significant differencebetween the group II and the control group. Conclusion: It was possible that the complete damage of autonomic nervous sys-tem function occurred in GD patients before treatment,but the patients obviously recovered after treatment. These changesmight be correlated with the thyroid hormone in blood which stimulated the cardiac autonomic nerves.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 135-136 )