Prognostic Significance of Megakaryocyte Number in Children with Idiopathic Thrombocytopenic Purpura
Abstract:Objective: To investigate the prognostic significance of bone marrow megakaryocyte number in children with idiopathic
thrombocytopenic purpura (ITP). Methods:Fifty patients were divided into two groups which included normal (group 1)
and abnormal (group 2) number of megakaryocyte groups according to megakaryocyte counting, and received the same
treatment with the follow-up of 1 year. Results:The complete remission was 77.8% in group I and 39.1% in group 2 two
weeks after treatment ( x2 = 7.72, P<0.01). The complete remission rates of platelet in group 1 and group 2 were 85.1%
and 56.5% respectively (x2 = 5.07,P<0.05).Eight patients developed to CITP,2 cases were from group 1,and 6 from
group 2. Conclusion:Bone marrow megakaryocyte number is a valuable marker in prognosis of ITP.
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Publication Date:2001-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:2( 74-75 )
