Analysis of the Related Influencing Factors and Preventive Strategies for Venous Thromboembolism after Gastrointestinal Surgery

ZHENG Nan; YAN Jianshan

doi:10.16458/j.cnki.1007-0893.2025.24.003

Abstract：Objective To explore the related influencing factors of venous thromboembolism(VTE)in patients after gastrointestinal surgery and propose targeted preventive strategies.Methods A retrospective analysis was conducted on the clinical data of 120 patients who underwent gastrointestinal surgery in Jian'ou Municipal Hospital from June 2024 to June 2025.The patients were divided into a VTE group(26 cases)and a non-VTE group(94 cases)based on whether VTE occurred within 14 days after surgery.General patient information,surgical-related indicators,laboratory indicators,and postoperative care indicators were collected.Univariate analysis was first used to screen the factors that might affect the occurrence of VTE after surgery,and then multivariate Logistic regression analysis was performed on the factors with statistical significance to identify the independent risk factors for VTE after surgery.Results Among the 120 patients who underwent gastrointestinal surgery,26 developed VTE within 14 days after surgery,with an incidence rate of 21.67%.Univariate analysis showed that there were statistically significant differences in age≥60 years,diabetes mellitus,operation duration≥3 hours,preoperative D-dimer level>0.5 mg·L-1,and postoperative bed rest time≥72 hours between the two groups(P<0.05).Logistic regression analysis results indicated that age≥60 years(OR=5.259,95%CI:2.002～13.816),diabetes mellitus(OR=2.750,95%CI:1.131～6.688),operation duration≥3 hours(OR=7.471,95%CI:2.716～20.551),postoperative bed rest time≥72 hours(OR=14.600,95%CI:4.912～43.398),and preoperative D-dimer level>0.5 mg·L-1(OR=14.385,95%CI:4.522～45.760)were independent risk factors for VTE after gastrointestinal surgery(P<0.05 and OR>1).Conclusion The occurrence of VTE after gastrointestinal surgery is closely related to age,history of diabetes,operation duration,postoperative bed rest time,and preoperative D-dimer level.Clinical individualized preventive strategies should be formulated based on these risk factors to reduce the risk of VTE after surgery.