Investigation on the Nutritional Status Characteristics and Influencing Factors of Patients with Endometrial Cancer after Adjuvant Chemotherapy

HUANG Yujie; DU Xinyang; WEN Fengxiang

doi:10.16458/j.cnki.1007-0893.2025.23.003

Abstract：Objective To explore the nutritional status and influencing factors of patients with endometrial cancer after adjuvant chemotherapy.Methods A total of 104 patients with endometrial cancer who received adjuvant chemotherapy at Nanyang Central Hospital from March 2023 to March 2025 were selected as the research subjects.According to the patient-generated subjective global assessment(PG-SGA)score,they were divided into a good nutritional status group(58 cases,total score<4)and a malnutrition group(46 cases,total score≥4).The general data and nutritional indicators[serum total protein(TP),albumin(ALB),prealbumin(PAB)levels]of the two groups were compared,and Logistic regression analysis was used to analyze the factors influencing the nutritional status of patients with endometrial cancer after adjuvant chemotherapy.Results There were statistically significant differences in age,body mass index(BMI),chemotherapy stage,whether diabetes was combined,whether there were gastrointestinal reactions,coping styles,and the proportion of taste changes between the two groups(P<0.05);the levels of serum TP,ALB,and PAB in the malnutrition group were lower than those in the good nutritional status group,and the differences were statistically significant(P<0.05);multivariate Logistic regression analysis showed that advanced chemotherapy stage,combined diabetes,and negative coping style were independent risk factors affecting the nutritional status of patients with endometrial cancer after adjuvant chemotherapy(P<0.05).Conclusion Advanced chemotherapy stage,combined diabetes,and negative coping style are independent risk factors affecting the nutritional status of patients with endometrial cancer after adjuvant chemotherapy.