Potential Profile Analysis of Fear of Disease Progression in Patients with Cervical Cancer and Implications for Nursing

LUO Lu; LI Qiuyuan

doi:10.16458/j.cnki.1007-0893.2025.19.002

Abstract：Objective To analyze the latent profiles of fear of cancer progression(FCP)in patients with cervical cancer and explore the influencing factors,providing a basis for targeted nursing interventions in clinical practice.Methods A cross-sectional survey design was adopted.A total of 236 patients with cervical cancer who were hospitalized in the gynecological oncology department of Xuchang Central Hospital from August 2024 to May 2025 were selected as the research subjects.Data were collected using the fear of cancer progression short form,the chinese version of the impact of event scale-revised,and the Chinese version of the painful disclosure index scale.Latent profile analysis was used to identify the latent classes of FCP.Logistic regression analysis was conducted to screen the factors influencing the FCP classes.Results Through latent profile analysis,three latent profiles of FCP in patients with cervical cancer were identified,namely,the low fear group(70 cases,29.66%),the moderate fear group(94 cases,39.83%),and the high fear group(72 cases,30.51%).Univariate analysis showed that age,educational level,per capita monthly family income,pathological stage,comorbidities,disease understanding,negative cognitive processing,and painful disclosure were all influencing factors of FCP classes(P<0.05).Multivariate Logistic regression analysis indicated that pathological stage,comorbidities,disease understanding,negative cognitive processing,and painful disclosure were independent influencing factors of FCP classes(P<0.05).Conclusion Patients with cervical cancer have different latent profiles of FCP,which are related to multiple factors.In clinical nursing practice,individual differences among patients should be emphasized.Particularly for those with advanced pathological stages,multiple comorbidities,insufficient disease understanding,severe negative cognitive processing,and weak painful disclosure ability,personalized psychological support and nursing interventions should be provided to improve their mental health and quality of life.