A Meta-analysis of the Impact of Advance Care Plans on End-of-life Treatment Preferences in Patients with Heart Failure
JIANG Xiaolan
YU Cong
ZHAO Yunxiao
KONG Wenxuan
YAO Mengting
LUO Xiufang
Abstract：Objective To systematically evaluate the impact of advance care planning(ACP)on the end-of-life treatment preferences of patients with heart failure(HF),and to provide a reference basis for related research.Methods Computer retrieval was conducted in PubMed,Web of Science,Cochrane Library,Embase,China National Knowledge Infrastructure(CNKI),VIP Database,and Wanfang Database to collect randomized controlled trials(RCTs)comparing the impact of ACP intervention and conventional care on end-of-life treatment preferences in HF patients,with the study subjects being HF patients,published from the establishment of the databases to October 23,2024.Meta-analysis was performed using RevMan 5.3 software.Results A total of 7 literatures were included,involving 1145 patients with HF.The results of the meta-analysis showed that ACP could influence the end-of-life treatment preferences of HF patients.After the intervention,the end-of-life treatment of patients was more inclined to pursue comfortable care and reduce life-prolonging treatment[SMD=0.49,95%CI(0.44-0.53),Z=19.77,P<0.00001].Conclusion ACP can have an impact on the end-of-life treatment preferences of HF patients,making them more inclined to pursue comfortable care in end-of-life treatment rather than blindly undergoing meaningless life-prolonging treatment.Future research should further explore the optimal implementation timing and methods of ACP,thereby maximizing its positive effects on end-of-life care for patients with HF.
Keywords：Advance care planHeart failureEnd-of-life treatment preferenceMeta-analysis
Publication Date：2025-05-30
Online Publishing Date：2025-09-15(First online date of this platform, not the publication date of the document)
Pages：5( 23-26,后插8-后插10 )