The Effect of Jianpi Yiqi Decoction Combined with RPH on Rectal Physiological Function and Inflammatory in Patients with Internal Rectal Mucosal Prolapse

LI Peng; CHEN Liping; HUANG Jintao

doi:10.16458/j.cnki.1007-0893.2024.19.003

Abstract：Objective To explore the effect of Jianpi Yiqi Decoction combined with Rubber Band Ligation(RPH)on rectal physiological function and stress indices in patients with internal rectal mucosal prolapse.Methods A total of 82 patients with Qi deficiency and sinking type internal rectal mucosal prolapse were selected from Longyan People's Hospital from January 2022 to January 2024 as the research subjects.They were divided into operation group and formula group using the ball method,with 41 cases in each group.Patients in the operation group received RPH treatment,while patients in the formula group received additional treatment with Jianpi Yiqi Decoction based on the operation group.The traditional Chinese medicine(TCM)symptom score,clinical efficacy,inflammatory factor,and rectal physiological function were compared between the two groups.Results At 3 weeks postoperatively,the scores for anal distension,difficulty in defecation,and shortness of breath in the formula group were lower than those in the operation group,with statistically significant differences(P<0.05).The total effective rate of treatment in the formula group was 90.24%(37/41),higher than 70.73%(29/41)in the operation group,with statistically significant difference(P<0.05).At 1 week postoperatively,the levels of serum tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and C-reactionprotein(CRP)in the formula group were lower than those in the operation group,with statistically significant differences(P<0.05).At 6 months postoperatively,the maximum systolic pressure and maximum resting pressure of the rectum in the formula group were higher than those in the operation group,and the rectal sensory capacity was lower than that in the operation group,with statistically significant differences(P<0.05).Conclusion Jianpi Yiqi Decoction combined with RPH can improve the rectal physiological function of patients with internal rectal mucosal prolapse,regulate TCM symptom scores,control inflammatory factor,and enhance clinical efficacy.