The Diagnostic Value of Contrast Enhanced Ultrasound in BI-RADS Class 4 Breast Cystic and Solid Lesions
CHEN Kehua
JIN Chunchun
XU Lifeng
LU Jianghao
MA Yuanyuan
MA Yuqin
ZHOU Peng
Abstract：Objective To explore the diagnostic value of conventional ultrasound(US)and US combined with contrast-enhanced ultrasound(CEUS)for breast imaging reporting and data system(BI-RADS)class 4 breast cystic and solid lesions.Methods A retrospective analysis was conducted on 116 patients with breast cystic solid lesions classified as BI-RADS 4 who underwent US and CEUS at Shenzhen Second People's Hospital from August 2017 to January 2024.Blind analysis of static images and dynamic videos of US and CEUS was used,with pathology obtained through puncture biopsy or surgery as the gold standard.Clinical data and differences in US and CEUS indicators were compared between benign and malignant groups.The receiver operating characteristic(ROC)curve was constructed,and the BI-RADS classification was adjusted after CEUS to compare the diagnostic efficacy of US and US combined CEUS.Results Among 116 cases of breast lesions,90 cases were benign and 26 cases were malignant.There were statistically significant differences between two groups of breast cystic and solid lesions in terms of age,maximum diameter,shape,boundary,boundary of cystic and solid components,calcification,blood flow,edge of solid component enhancement,expansion of solid part enhancement,extension of solid part enhancement beyond the base,angle between solid part and tumor wall,and thickening of enhanced wall and/or partition(P<0.05).The area under the ROC curve,sensitivity,specificity,and accuracy of US and US combined with CEUS in diagnosing breast cystic and solid lesions were(0.682,34.62%,65.56%,and 58.62%),(0.898,88.46%,86.67%,87.07%)respectively.After CEUS,the BI-RADS classification was readjusted to BI-RADS 4B as the biopsy threshold,and the biopsy rate decreased from 100%to 30.17%.Conclusion CEUS has important value in distinguishing between benign and malignant breast cystic lesions,and can provide important imaging evidence for clinical practice.
Keywords：Contrast-enhanced ultrasoundBreast imaging reporting and data system class 4Breast cystic and solid lesions
Publication Date：2024-09-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 63-66,后插6,封3 )