Comparison of the Effects of Carbon Dioxide Pneumoperitoneum Laparoscopic Surgery and Laparotomy on Patients with Bacterial Peritonitis
WU Jun qiang
PENG Huai du
CHI Rui zhong
Abstract：ObjectiveTo explore the effects of carbon dioxide pneumoperitoneum laparoscopic surgery and laparotomy on systemic inflammatory reaction and bacterial translocation in patients with postoperative bacterial peritonitis, so as to provide a reference for improving the treatment of bacterial peritonitis. Methods66 patients with bacterial peritonitis were randomly divided into laparoscopic surgery group and laparotomy group, with 33 in each group. Blood culture, white cell count (WBC), blood levels of C _ reactive protein (CRP), tumour necrosis factor (TNF) and interleukin _ 6 (IL _ 6) before operation and 1 day or 3 days after operation were measured. Incidences of incisional infection and abdominal abscess were observed. ResultsThere was no signiifcant difference in clinical features and laboratory indices between the two groups before operation (allP<0.05). Similar incidences of bacterial translocation to liver, spleen, lungs and kidneys were observed in both groups (allP>0.05). Noticeably, blood levels of WBC, CRP, TNF and IL _6 were signiifcantly lower in patients of laparoscopic surgery group than those in laparotomy group (P<0.05 orP<0.01).Conclusion Short _ term effects of carbon dioxide pneumoperitoneum laparoscopic surgery and laparotomy are similar on patients with bacterial peritonitis. However, systemic inlfammatory reaction can signiifcantly inhibited in patients treated by carbon dioxide pneumoperitoneum laparoscopic surgery, so this therapy is worth further research and promoting in clinical practice.
Keywords：Laparoscopic surgeryCarbon dioxide pneumoperitoneumBacterial peritonitisLaparotomy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 9-10,18 )