Interpretation of《Guidelines for diagnosis and nutritional intervention of mild to modetate non-IgE medi-ated cow's milk protein allergy in Chinese infants》
PANG Huanxiang
ZHOU Zhen
LIN Ying
TAN Yanfang
GAO Jie
ZHANG Yuzhen
LIU Wangkai
Abstract：Cow's milk protein allergy(CMPA)is an abnormal immune response triggered by cow's milk proteins.Clinically,CMPA can be categorized into immediate-onset IgE-mediated,delayed-onset non-IgE-mediated,or mixed forms.Although several expert consensus statements on CMPA have been published in China,they often fail to clearly differentiate between IgE-mediated and non-IgE-mediated subtypes.Non-IgE-mediated CMPA is more prevalent in infants;however,due to the absence of specific clinical manifestations and standardized diagnostic approaches,its diagnosis and management remain significant clinical challenges.To facilitate the standardized diagnosis and management of non-IgE-mediated CMPA in infants,a multidisciplinary panel of experts convened by the Allergy Prevention and Control Professional Committee of the Chinese Preventive Medicine Association has developed the"Guidelines for Diagnosis and Nutritional Intervention of Mild to Moderate Non-IgE-Mediated Cow's Milk Protein Allergy in Chinese Infants."This article presents and interprets the key recommendations of the guideline,focusing on clinical features,diagnostic procedures,nutritional management,and complementary feeding strategies for infants with mild to moderate non-IgE-mediated CMPA.
Keywords：cow's milk protein allergyinfantnon-IgE mediateddiagnostic processnutritional management
Publication Date：2025-12-25
Online Publishing Date：2026-01-04(First online date of this platform, not the publication date of the document)
Pages：9( 3793-3801 )