Research progress of CAR-T cell therapy in bladder cancer
HU Zongjian
WAN Shun
YANG Jianwei
WANG Li
CHEN Siyu
YANG Li
Abstract：Bladder cancer(BCa)is a common malignant tumor of the urinary system,and its conventional treatment methods have many limitations.Chimeric antigen receptor T cell(CAR-T)therapy,as an emerging immunotherapy method,has achieved significant success in hematological malignancies and has brought new hope for the treatment of solid tumors.This article reviews the research progress of CAR-T cell therapy in the treatment of BCa,including the basic structure of CAR-T cells,potential therapeutic targets in bladder cancer,current chal-lenges and corresponding strategies.
Keywords：chimeric antigen receptor T cellbladder cancerimmunotherapy
Publication Date：2025-11-25
Online Publishing Date：2025-12-02(First online date of this platform, not the publication date of the document)
Pages：5( 3496-3500 )