Relationship between left ventricular hypertrophy and galactose 3 and microalbuminuria in elderly patients with hypertension
ZHU Lei
YANG Ming
CHENG Bo
XU Yan
YAO Feng
ZOU Yong
ZHANG Suchuan
LIU Min
Abstract:Objective To investigate the relationship of galectin 3(Gal-3)and microalbuminuria(MAU) with left ventricular hypertrophy(LVH)in elderly patients with hypertension. Methods 120 patients with LVH were included in the study as LVH group and another patients with non-LVH group as NLVH group with the age, sex ratio and length of stay matched to the LVH group.The conditional Logistic regression was used to analyze the independent risk factors of LVH.Results The single factor analysis showed a positive correlation of LVH with the course of disease,blood pressure control,BMI,NT-proBNP,Gal-3,MAU and education level. By multivariate Logistic regression,course of disease,blood pressure,Gal-3 and MAU were included in the model,with the OR (95% CI)of 1.062(1.001~2.237),1.643(1.527~5.185),2.816(2.231~8.872)and 3.736(3.151~11.391). Conclusion As independent risk factors,the course of disease,control of blood pressure,Gal-3 and MAU are significantly correlated with LVH.
Keywords:galactoselectin-3microalbuminuriahypertensionleft ventricular hypertrophy
Publication Date:2018-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 247-250 )
