Assessment of intensive statin therapy in hospitalized patients with acute myocardial infarction and its influence factors
QU Huan
Abstract：Objective To explore the status quo of intensive statin therapy in hospitalized patients with acute myocardial infarction (AMI) from 2001 to 2011 and analyze its influence factors.Methods We obtained in-formation of AMI patients in 2001,2006,and 2011 from their medical record. Intensive statin therapy was defined as statin regiments with expected LDL-C lowering of at least 40%.Results Among 767 patientswith definite dosage of statin,the use frequencyof intensive statin increased from 0%in 2001 to 60.77% in 2006,and 88.71% in 2011 (P<0.0001).Morefemalesreceived intensive statin therapy than males(P=0.015)and the use frequency of intensive statin therapy in smoking patients was obviously more frequent than that in hypertension ,diabetes mellitus and hy-perlipidemia patients (P=0.0081).The use frequency of intensive statin therapy in patients with ischemic stroke was significantly lower than that in those with AMI or coronary artery disease(P=0.0437). AMI patients with STele-vatedwere much less likely received intensive statin therapy than those with non-ST elevated(P<0.0001). Chest pain,cardiac shock or cardiac arrest and the base level of LDL-C exerted no influence on the use of intensive statin therapy(P>0.05). Conclusions The use frequency of intensive stain therapy among AMI patientsincreasesyear by year and it is affected by sex,risk factors,history of disease and type of infarction.
Keywords：acute myocardial infarctionintensive statin therapylipids
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 2492-2496 )