Expressions and significances of prognosis by MiR-451a in nasopharyngeal carcinoma in Guangxi
MO Xiang-lan
YIN Wu
WEI Hai-ming
LAN Gui-ping
SI Yong-feng
ZHOU Min-yan
Abstract：Objective To investigate the expression level and the significances of prognosis by miR-451a in nasopharyngeal carcinoma (NPC) in Guangxi. Methods The expressions of miR-451a in 89 cases of nasopharyngeal carcinoma were detected by real time RT-PCR. The relation among the expression level , the clinicopathologic features of NPC and its prognosis were analyzed. Results The expression of miR-451a were found in all of nasopharyngeal carcinoma. The expression level of miR-451a in nasopharyngeal carcinoma was negative correlated to overall survival and disease free survival (P = 0.01,P = 0.04). Conclusions miR-451a may play a key role in detection of nasopharyngeal carcinoma with poor prognosis.
Keywords：Nasopharyngeal carcinomaMiR-451aReal time RT-PCRPrognosis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2462-2464 )