Impact of collateral circulation on neurological function and prognosis outcome of patients with acute cerebral infarction

ZHANG Qi-ping; CHEN Ying-dao; LI Yu-ying; LI Hai-ning; LIANG Bing-song; LI Jian

doi:10.3969/j.issn.1006-5725.2016.07.002

Abstract：Objective To investigate the impact of collateral circulation on neurological function and prognosis outcome of patients with acute cerebral infarction. Methods Assessed the collateral circulation of 274 patients with acute cerebral infarction from June 2012 to April 2015 in the department of neurology in Worker′s Hospital of Wuzhou using DSA, analyzed patients′ neurological function and prognosis outcome concerning their collateral circulation. Results (1) Impairment of neurological function were different between collateral circulation group and non-collateral circulation group ( P < 0 . 05 ) , but there was no significant difference in neurological impairment between the primary collateral circulation and secondary collateral circulation (P > 0.05). (2)14 and 90 days after treatment, symptoms of neurological impairment in posterior communicating artery, before pial artery, after pial artery and combination artery were significantly improved as with their NIHSS scores (P<0.05). However, symptoms of neurological impairment in anterior communicating artery, arteria ophthalmica and non-collateral circulation did not significantly improved at 14 and 90 days after treatment, with no significantly different NIHSS score (P > 0.05). Conclusions (1) Neurological function of patients with collateral circulation was better without collateral circulation. Grading of collateral circulation had did not relate to neurological function. (2) Prognosis of patients with collateral circulation was improved significantly than the patients without collateral circulation. The types of collateral circulation affect the prognosis of the patients with acute cerebral infarction.