The roles of anti-inflammation and analgesia of Qinghouxiaoyan granules
HUANG Le-shan
HUANG Han-hui
WU Yue-hong
YAN Peng-ke
Abstract：Objective To assess the anti-inflammatory and analgesic efects of Qinghouxiaoyan granules. Methods The rats were divided into blank group , Qinghouxiaoyan granules of high , medium , or low dose group, and aspirin group. Xylol-induced auricle swelling, carrageenan-induced paw swelling, Hac-induced blood capillary lealkage , and cotton pellet-induced graunloma were performed to assess the inflammatory effect; heat-plate test and Hac induced-twisting method were used to observe the analgesic efect. Results Qinghouxiaoyan granules played significant inhibitory action on xylene-induced inflammation , carrageenan-induced inflammation , and cotton-ball-induce granulation edema in different degrees; and decreased HAc-induced abdominal capillary permeability. The granules also showed significant analgesic effects on pain induced by heat and chemical stimu-lation in rats. Conclusion Qinghouxiaoyan granules has significant anti-inflammatory and analgesic effects.
Keywords：Qinghouxiaoyan granulesAnti-inflammationAnalgesia
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 3843-3846 )