Comparison of the safty of different assisted reproductive technologies
Abstract：Objective To compare the pregnancy outcomes of in vitro fertilization- embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI). Methods A retrospective analysis from January 2010 to January 2014 for 9 973 IVF-ET and 1 368 ICSI treatment cycles were collected. In the IVE and ICSI groups , we compared the implantation, clinical pregnancy, multiple pregnancy, ectopic pregnancy, abortion, premature birth, malformation rates, and sex ratio. Results The implantation rate (33.42%, 31.53%), clinical pregnancy rate (50.00%, 47.30%), abortion rate (13.93%, 11.50%), premature birth rate (25.04%, 23.26%), sex ratio (115:100, 103:100) and malformation rates (1.05%, 0.76%) were no statistically significant between the IVF-ET group and the ICSI group (P>0.05). The ectopic pregnancy rate (3.75%, 1.76%), multiple pregnancy rate (38.54%, 32.44%), low birth weight infants rate (32.07%, 26.86%) were increased significantly in the IVF group than the ICSI group (P<0.05 or P<0.01). Conclusions IVF and ICSI micromanipulation did not increase the risk of pregnancy. But the multiple pregnancy rate, ectopic pregnancy rate,low birth weight infants rate were increased significantly in the IVF group than the ICSI group.
Keywords：Assisted reproductive technologiesIn vitro fertilization-embryo transferSingle sperm Injection in oocytesCongenital malformationsMultiple pregnancies
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2630-2633 )