Expression and clinical value of serum thymidine kinase 1 in patients with acute exacerbation of chronic obstructive pulmonary disease
LIU Yin
JIN Meng-meng
QIAN Zhen-dong
CHEN Mei-li
HUANG Rui
DU Ting
ZHANG Yan-bei
Abstract：Objective To investigate the relations and evaluation value of serum thymidine kinase 1 (sTK1) in the treatment of patients withacute exacerbation of chronic obstructive pulmonarydisease (AECOPD). Methods The retrospective treating studies were performed on 104 patients with AECOPD , sTK1 level was de-tected by chemiluminescence dot-blot assay before and after treatment , and the correlation between the expression of sTK1 and CRP after treatment in the two groups was analyzed. Results The levels of sTK1 and CRP in the ef-fective group significantly lowered after treatment (P < 0.05). The expression of sTK1 in the effective group and in the ineffective group after treatment was significantlycorrelated with CRP (P < 0.05). Conclusion sTK1 can be used as a valuable indicator to evaluate the severity of AECOPD and to estimate the efficacy of AECOPD thera-py.
Keywords：Acute exacerbation of chronic obstructive pulmonary diseaseSerum thymidine kinase 1Efficacy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1431-1433 )