Correlation between body mass index and insulin dose in type 2 diabetic patients with continuous subcutaneous insulin infusion
LIANG Cui-ge
DONG Qing-yu
DU Wen-hua
LIU Xiao-meng
LI Wen-xia
WANG Yue-li
GONG Qian
PAN Zhen-yu
GAO Guan-qi
Abstract：Objective To investigate the correlation between BMI and insulin dose in diabetic patients after short-term continuous subcutaneous insulin infusion (CSII). Methods Three hundred patients with type 2 diabetes mellitus (T2DM) were enrolled and randomized into the normal weight (BMI < 23 kg/m2) group, overweight (BMI 23 ~ 25 kg/m2) group and obesity (BMI≥25 kg/m2) group. The metabolic and anthropometric parameters of each group were compared and the related factors which may influence insulin dose were analyzed. Results The insulin dose per weight in the overweight group or in the obesity groups was significantly lower than that in the normal weight group. Weight and BMI were negatively correlated with the insulin dose per weigh. Conclusions Differences of glycemia level , β-cell function and insulin resistance exist in Chinese type 2 diabetes patients with different BMI. The stratification of BMI should be considered before estimating the insulin dose by body weight in CSII therapy.
Keywords：Diabetes mellitustype 2Body mass indexInsulin doseContinuous subcutaneous insulin infusion
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2408-2410 )