Mixed Porokeratosis:a Case Report
FENG Qing
YUAN Xuhai
JIN Jiang
ZHANG Jianzhong
ZHOU Cheng
CHEN Zhou
Abstract：This study reported a case of mixed porokeratosis.A 67-year-old female patient presented with vulvar and perianal rash and itching for three months.The patient was treated with surgery,chemotherapy and immune therapy for colorectal cancer one year earlier.Dermatological examination revealed the presence of well-defined red plaques with yellowish-white keratinous material on the vulva and perianal region.Brown,circumscribed papules and macules measuring 0.5-2.0 cm were seen on the inner thighs and groin,accompanied by dike-like elevations at the periphery of some rashes and a light-colored,smooth central region.Histopathological examination confirmed the diagnosis of porokeratosis.The patient was administered oral acitretin at a dosage of 10 mg daily,and a topical combination of triamcinolone acetonide and econazole cream on the affected areas.Following one month of treatment,the majority of the rashes had subsided,and pruritic symptoms were completely resolved.
Keywords：mixedporokeratosisrectal cancer
Publication Date：2026-02-10
Online Publishing Date：2026-03-17(First online date of this platform, not the publication date of the document)
Pages：3( 83-85 )