Clinical Efficacy of Qingfeng Jiedu Method Combined with Narrowband UVB for Psoriasis Vulgaris with Blood-Heat Syndrome

TIAN Jun; SHI Yaling; WANG Xiyan; YANG Li

doi:10.11786/sypfbxzz.1674-1293.20260112

Abstract：Objective To evaluate the clinical efficacy and immunological effects of the Qingfeng Jiedu traditional Chinese medicine method combined with narrowband ultraviolet B(NB-UVB)therapy in patients with psoriasis vulgaris characterized by blood-heat syndrome.Methods We retrospectively reviewed 112 patients with psoriasis vulgaris of blood-heat syndrome treated at Shaanxi Provincial People's Hospital from December 2023 to November 2024.Based on received treatment,patients were assigned to an observation group(NB-UVB plus Qingfeng Jiedu method,n=57)or a control group(NB-UVB alone,n=55).Both regimens were administered for 8 consecutive weeks.Outcomes included overall clinical response and adverse events,traditional Chinese medicine(TCM)syndrome scores,disease severity measured by the Psoriasis Area and Severity Index(PASI),and immune-function(CD3+,CD4+/CD8+ratio,and natural killer[NK]cell levels)before and after treatment.Results Both groups showed significant post-treatment reductions in TCM syndrome scores and PASI(P<0.05);reductions were significantly greater in the observation group(P<0.05).CD3+counts and CD4+/CD8+ratios declined in both groups after therapy(P<0.05),with larger decreases observed in the observation group(P<0.05).NK cell levels increased significantly in both groups(P<0.05),with a greater rise in the observation group(P<0.05).The overall effective rate was higher in the observation group(96.49%)than in the control group(83.64%)(P<0.05).Adverse event rates were 12.28%in the observation group and 7.27%in the control group,with no statistically significant difference between groups(P>0.05).Conclusion The Qingfeng Jiedu method combined with NB-UVB is a safe and effective treatment for psoriasis vulgaris with blood-heat syndrome and may modulate immune function.