Analgesic effect and Safety of Chloral Hydrate Sedation Combined with Local Anesthesia via Lidocaine and Restraint Band Fixation for Removing Benign Skin Masses in Infants and Young Children
JIANG Lixiao
LIU Xiaoyan
ZHANG Gaolei
QIN Qin
ZHANG Haihua
CAO Huina
WANG Yuhan
DENG Wei
LI Qian
Abstract：Objective To investigate the sedative effect and safety of chloral hydrate combined with local anesthesia via subcutaneous injection of lidocaine and restraint band fixation in infants undergoing skin mass excision.Methods Fifty-six infants and young children receiving chloral hydrate sedation combined with local anesthesia via subcutaneous injection of lidocaine and restraint band fixation for removing benign skin masses at the Second Department of Dermatology,Capital Center for Children's Health,Capital Medical University from May 2023 to April 2024 were included in the observation group.The other 24 infants with skin mass excision under local anesthesia via subcutaneous injection of lidocaine and restraint band fixation were included in the control group.Vital signs like heart rate and respiratory rate were monitored at 20-30 minutes after medication.Success sedation to fall asleep was observed.The duration from local anesthesia to fall asleep,and the operation status were recorded.Intraoperative blood loss and surgery time were recorded after surgery.Infection status,and wound healing time were recorded at 2 weeks postoperatively.Scar hyperplasia and aesthetic satisfaction of guardians were recorded at 3-6 months postoperatively.Results Among the 56 children in the observation group,the sedation success rate reached 94.64%(53/56),with an average time to fall asleep of 8.5 min.In this group,83.02%(44/53)of infants maintained sleep state throughout the surgery to ensure the smooth completion of the fine operation.Among the 24 children in the control group,only 2(8.33%,2/24)fell asleep throughout the whole process and met the fine operation requirements.Significantly shorter operation duration,less intraoperative blood loss,lower respiratory rate,shorter wound healing,lower incidence of scar hyperplasia,and higher aesthetic satisfaction were detected in the observation group than the control group(P<0.05).The incidence of postoperative infection was lower in the observation group than the control group,without a significant difference(P=0.309).Conclusion Chloral hydrate combined with local anesthesia via subcutaneous injection of lidocaine and restraint band fixation in infants can enable infants and young children with benign skin mass excision to fall asleep quickly and smoothly,and significantly improve the fineness and success rate of the surgery.It has a slight impact on the circulation and respiratory system,and can reduce the risk of postoperative infection,promote wound healing,and improve postoperative aesthetic effect.
Keywords：skin surgerychloral hydratelidocaineinfants and young childrensedation
Publication Date：2026-02-10
Online Publishing Date：2026-03-17(First online date of this platform, not the publication date of the document)
Pages：6( 6-11 )