Application of Exosomes in Cosmetic Dermatology: A Review of Advantages and Challenges
Abstract：Exosomes, as extracellular vesicles of 30-150 nm in size, mediate intercellular communication by transporting proteins, lipids, and nucleic acids, and have shown unique value in skin health and beauty. Their innovation lies in overcoming the limitations of traditional cell therapy, exerting regenerative effects in a 'cell-free' form. For example, exosomes derived from mesenchymal stem cells (MSCs) can promote collagen synthesis by inhibiting matrix metalloproteinases (MMPs), improving skin aging. Plant-derived extracellular vesicles (PDENs), on the other hand, avoid ethical and immune risks associated with human-derived exosomes, offering new directions for regulating pigment metabolism (such as delivering vitamin C to inhibit tyrosinase activity).
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Publication Date：2025-12-10
Online Publishing Date：2026-01-04(First online date of this platform, not the publication date of the document)
Pages：1( 496 )