Clinical Characteristics of 32 Cases with Cutaneous Mycobacterial Infection
DONG Jiacheng
MAO Jinzhu
Abstract：Objective To analyze the clinical characteristics of cutaneous mycobacterial infection cases and explore their epidemiological features,diagnosis,and treatment.Methods A retrospective clinical analysis was performed on 32 patients diagnosed with cutaneous mycobacterial infections in the Department of Dermatology,the First Affiliated Hospital of Soochow University,between January 2023 and January 2025.Clinical features,pathogen identification,treatment regimens,and outcomes were analyzed.Results Among the 32 confirmed patients,the male-to-female ratio was 15∶17,with the majority predominantly aged 60-75 years.A definite history of trauma was documented in 78.13%(25/32)of cases.Mycobacterial nucleic acid sequencing yielded positive results in 100%(32/32)of patients,while mycobacterial tissue culture was positive in 59.38%(19/32).Mycobacterium marinum(75.00%,24/32)was the most prevalent pathogen,followed by Mycobacterium chelonae(12.50%,4/32).All evaluable patients(11 were lost to follow-up)achieved successful treatment outcomes.Conclusion Cutaneous mycobacterial infections primarily affect middle-aged and elderly individuals,show no significant gender predilection,and are frequently associated with a history of trauma.Nucleic acid sequencing significantly enhances detection sensitivity.Mycobacterium marinum is currently the most common causative pathogen identified at our institution,and most infections are curable with standardized treatment regimens.
Keywords：cutaneous mycobacterial infectionskinclinical characteristicsdiagnostic methodsepidemiology
Publication Date：2025-12-10
Online Publishing Date：2026-01-04(First online date of this platform, not the publication date of the document)
Pages：4( 440-443 )